Tier B — topicalTier C — injectable

GHK-Cu

Copper tripeptide (glycyl-L-histidyl-L-lysine + Cu²⁺). Occurs naturally in human plasma; concentration declines with age.

Conceptual chain illustration for GHK-Cu — for representation purposes only. Not the compound's verified molecular structure.

Evidence

Real human data exists — for topical, cosmetic use. Studies on skin appearance, collagen, and wound healing. Widely used in legitimate cosmeceuticals. Injectable use has no comparable human trial evidence — what exists there is preclinical.

The distinction that matters

Topical human evidence does not transfer to injectable use. Different route, different systemic exposure, different safety profile. See the full breakdown in our mechanism explainer on this exact issue.

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